Definitions

Pills: https://pubmed.ncbi.nlm.nih.gov/12624633/ Abstract Deep vein thrombosis (DVT) is a common disease with an annual incidence of about 1 in 1000. Many risk factors have already been studied, both genetic and acquired. It is unclear whether obesity affects thrombotic risk in unselected patients. Obesity is common, with a prevalence of 20-25% and may therefore have a […]

Joint replacement: https://pubmed.ncbi.nlm.nih.gov/11114314/ Abstract Background: Recent studies have shown that symptomatic venous thromboembolism after total hip arthroplasty most commonly develops after the patient is discharged from the hospital. Risk factors associated with these symptomatic thromboembolic events are not well defined. Methods: Using administrative data from the California Medicare records for 1993 through 1996, we identified 297 patients […]

Usefulness of clinical predictors for preoperative screening of deep vein thrombosis in hip fractures Kitchai Luksameearunothai 1 2, Paphon Sa-Ngasoongsong 3, Noratep Kulachote 1, Sorawut Thamyongkit 1 4, Praman Fuangfa 5, Pongsthorn Chanplakorn 1, Patarawan Woratanarat 1, Chanyut Suphachatwong 1   PMID: 28532441. PMCID: PMC5440897. DOI: 10.1186/s12891-017-1582-5 Abstract Background: Recent studies showed that preoperative deep vein thrombosis (DVT) was common after hip fracture (HF), and preoperative DVT screening has been recommended for preventing the fatal DVT-related […]

Frequency and Risk Factor of Lower-limb Deep Vein Thrombosis after Major Orthopedic Surgery in Vietnamese Patients My Hanh Bui 1, Duong Duc Hung 2, Pham Quang Vinh 3, Nguyen Hoang Hiep 4, Le Lan Anh 3, Toi Chu Dinh 3 PMID: 32215072. PMCID: PMC7084020. DOI: 10.3889/oamjms.2019.369 Abstract Background: Deep venous thrombosis (DVT) is a prevalent […]

Implementation and Validation of the 2013 Caprini Score for Risk Stratification of Arthroplasty Patients in the Prevention of Venous Thrombosis Eugene S Krauss 1, Ayal Segal 1, MaryAnne Cronin 2, Nancy Dengler 1, Martin L Lesser 3, Seungjun Ahn 3, Joseph A Caprini 2 4   PMID: 30939898. PMCID: PMC6714918. DOI: 10.1177/1076029619838066 Erratum in Corrigendum. […]

Persistent antiphospholipid antibody (aPL) in asymptomatic carriers as a risk factor for future thrombotic events: a nationwide prospective study P Mustonen 1, K V Lehtonen 2, K Javela 3, M Puurunen 4 PMID: 25164304. DOI: 10.1177/0961203314545410 Abstract Objectives: The long-term prognosis of individuals fulfilling the laboratory criteria, but not clinical criteria, of antiphospholipid syndrome (APS) has not been widely investigated. The primary aim of this […]

Thromboprophylaxis in Pregnancy Diana Kolettis 1, Sabrina Craigo 2 PMID: 29747737. DOI: 10.1016/j.ogc.2018.01.007 Abstract Venous thromboembolism is a leading cause of maternal morbidity and mortality worldwide. Identifying women who are at greatest risk for venous thromboembolism, and managing their pregnancies with appropriate thromboprophylaxis is essential to decreasing this life-threatening condition. Those at greatest risk are patients with thrombophilias, a personal […]

Use of hormone replacement therapy and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases Yana Vinogradova 1, Carol Coupland 2, Julia Hippisley-Cox 2 PMID: 30626577. PMCID: PMC6326068. DOI: 10.1136/bmj.k4810 Erratum in Use of hormone replacement therapy and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases. [No authors listed]BMJ. 2019 Jan 15;364:l162. doi: 10.1136/bmj.l162.PMID: 30647094 Free […]

Mechanisms of estrogen-induced venous thromboembolism Svetlana N Tchaikovski 1, Jan Rosing PMID: 20163835. DOI: 10.1016/j.thromres.2010.01.045 Abstract The use of oral contraceptives (OC) is a well established risk factor for venous thrombosis. It has been known for many years that almost all haemostatic parameters i.e. plasma levels of coagulation factors, anticoagulant proteins and proteins involved in the fibrinolytic pathway change […]

Different combined oral contraceptives and the risk of venous thrombosis: systematic review and network meta-analysis Bernardine H Stegeman 1, Marcos de Bastos, Frits R Rosendaal, A van Hylckama Vlieg, Frans M Helmerhorst, Theo Stijnen, Olaf M Dekkers PMID: 24030561. PMCID: PMC3771677. DOI: 10.1136/bmj.f5298 Abstract Objective: To provide a comprehensive overview of the risk of venous thrombosis in women using different combined oral contraceptives. Design: Systematic review and […]

Combined oral contraceptives, thrombophilia and the risk of venous thromboembolism: a systematic review and meta-analysis E F W van Vlijmen 1, S Wiewel-Verschueren 1 2, T B M Monster 3, K Meijer 1 PMID: 27121914. DOI: 10.1111/jth.13349 Abstract Essentials We performed a meta-analysis on thrombosis risk in thrombophilic oral contraceptive (COC)-users. The results support discouraging COC-use in women with a natural anticoagulant deficiency. Contrary, additive […]

Reference: Benjamin EJ, Muntner P, Alonso A, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Das SR, Delling FN, Djousse L, Elkind MSV, Ferguson JF, Fornage M, Jordan LC, Khan SS, Kissela BM, Knutson KL, Kwan TW, Lackland DT, Lewis TT, Lichtman JH, Longenecker CT, Loop MS, Lutsey PL, Martin SS, […]

Prevention of Venous Thromboembolism in Individuals with Spinal Cord Injury: Clinical Practice Guidelines for Health Care Providers, 3rd ed.: Consortium for Spinal Cord Medicine No authors listed PMID: 29339863. PMCID: PMC4981016. DOI: 10.1310/sci2203-209 See full article for guidelines. Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981016/ Reference: Top Spinal Cord Inj Rehabil. Summer 2016;22(3):209-240. doi: 10.1310/sci2203-209.

Venous thromboembolism after spinal cord injury Robert W Teasell 1, Jane T Hsieh, Jo-Anne L Aubut, Janice J Eng, Andrei Krassioukov, Linh Tu, Spinal Cord Injury Rehabilitation Evidence Review Research Team PMID: 19236977. PMCID: PMC3104991. DOI: 10.1016/j.apmr.2008.09.557 Abstract Objective: To review systematically the published literature on the treatment of deep venous thromboembolism after spinal cord injury (SCI). Data sources: MEDLINE/PubMed, CINAHL, EMBASE, and PsycINFO databases were searched […]

An economic evaluation of venous thromboembolism prophylaxis strategies in critically ill trauma patients at risk of bleeding T Carter Chiasson 1, Braden J Manns, Henry Thomas Stelfox PMID: 19554085. PMCID: PMC2695771. DOI: 10.1371/journal.pmed.1000098 Abstract Background: Critically ill trauma patients with severe injuries are at high risk for venous thromboembolism (VTE) and bleeding simultaneously. Currently, the optimal VTE prophylaxis strategy is unknown for […]

Venous thromboembolism after severe trauma: incidence, risk factors and outcome Thomas Paffrath 1, Arasch Wafaisade, Rolf Lefering, Christian Simanski, Bertil Bouillon, Timo Spanholtz, Sebastian Wutzler, Marc Maegele, Trauma Registry of DGU PMID: 19608183. DOI: 10.1016/j.injury.2009.06.010 Abstract Background: Venous thromboembolic events (VTEs) are common life-threatening complications after trauma, but epidemiology and reported risk factors still vary. The purpose of this investigation was to determine the incidence of VTEs […]

Investigation of the Incidence of Perioperative Pulmonary Embolism in Patients with Below-Knee Deep Vein Thrombosis after Lower Extremity Fracture and Evaluation of Retrievable Inferior Vena Cava Filter Deployment in These Patients Ye Pan 1, Jiacai Mei 1, Lei Wang 2, Mingzhe Shao 1, Jian Zhang 1, Haisheng Wu 1, Jun Zhao 3 PMID: 31075462. DOI: 10.1016/j.avsg.2019.02.027 Abstract Background: The objectives of the study were to investigate and compare the incidence of […]

Venous thromboembolism rates remained unchanged in operative lower extremity orthopaedic trauma patients from 2008 to 2016 Jared A Warren 1, Kavin Sundaram 2, Robert Hampton 3, Damien Billow 4, Brendan Patterson 5, Nicolas S Piuzzi 6 PMID: 31519436. DOI: 10.1016/j.injury.2019.09.003 Abstract Background: Venous thromboembolism (VTE) is a serious complication that contributes to morbidity, mortality, and healthcare costs during the surgical care of patient with lower extremity fractures. Despite this, […]

Hereditary thrombophilia Astrit Dautaj 1, Geraldo Krasi, Vilma Bushati, Vincenza Precone, Miriam Gheza, Francesco Fioretti, Marianna Sartori, Alisia Costantini, Sabrina Benedetti, Matteo Bertelli PMID: 31577252. PMCID: PMC7233636. DOI: 10.23750/abm.v90i10-S.8758 Abstract Thrombophilia is a group of disorders in which blood has an increased tendency to clot. It may be caused by inherited or acquired conditions. Thrombophilia is associated with risk of deep venous thrombosis and/or venous thromboembolism. Factor V […]

Venous Thromboembolism: Genetics and Thrombophilias Manila Gaddh 1, Rachel P Rosovsky 2 PMID: 33694139. DOI: 10.1055/s-0041-1723937 Abstract Venous thromboembolism (VTE) is a major cause of morbidity and mortality throughout the world. Up to one half of patients who present with VTE will have an underlying thrombophilic defect. This knowledge has led to a widespread practice of testing for such defects […]

Hypercoagulability Is a Stronger Risk Factor for Ischaemic Stroke than for Myocardial Infarction: A Systematic Review Alberto Maino 1, Frits R Rosendaal 2, Ale Algra 3, Flora Peyvandi 4, Bob Siegerink 5 PMID: 26252207. PMCID: PMC4529149. DOI: 10.1371/journal.pone.0133523 Abstract Background and purpose: Hypercoagulability increases the risk of arterial thrombosis; however, this effect may differ between various manifestations of arterial disease. Methods: In this study, we compared the effect of […]

Familial risk of venous thromboembolism in first-, second- and third-degree relatives: a nationwide family study in Sweden Bengt Zöller 1, Henrik Ohlsson, Jan Sundquist, Kristina Sundquist PMID: 23348971. DOI: 10.1160/TH12-10-0743 Erratum in Thromb Haemost. 2013 Jul 1;110(1):204 Abstract Venous thromboembolism (VTE) clusters in families, but the familial risk of VTE has only been determined in first-degree relatives. This nationwide study aimed […]

The value of family history as a risk indicator for venous thrombosis Irene D Bezemer 1, Felix J M van der Meer, Jeroen C J Eikenboom, Frits R Rosendaal, Carine J M Doggen PMID: 19307525. DOI: 10.1001/archinternmed.2008.589 Abstract Background: A positive family history of venous thrombosis may reflect the presence of genetic risk factors. Once a risk factor has been identified, it is […]

Efficacy of extended thrombo-prophylaxis in major abdominal surgery: what does the evidence show? A meta-analysis Federico Jorge Bottaro 1, Maria Cristina Elizondo, Carlos Doti, Julio Enrique Bruetman, Pablo Diego Perez Moreno, Eduardo Oscar Bullorsky, Jose Manuel Ceresetto Affiliations expand PMID: 18521515. DOI: 10.1160/TH07-12-0759 Abstract Venous thromboembolism (VTE) is a frequent complication following major abdominal surgery. The use of low-molecular-weight heparins (LMWH) to prevent thrombotic events […]

Postoperative venous thrombosis. Evaluation of five methods of treatment M Borow, H Goldson PMID: 6161550. DOI: 10.1016/0002-9610(81)90168-9 Abstract Five methods for preventing deep venous thrombosis in postoperative patients were evaluated and compared with a control group. Five hundred patients from five surgical specialties were studied. The incidence of deep venous thrombosis was 37.3 percent in the control group […]

Risk of venous thromboembolism associated with totally implantable venous access ports in cancer patients: A systematic review and meta-analysis Meng Jiang 1, Chang-Li Li 2, Chun-Qiu Pan 3, Xin-Wu Cui 1, Christoph F Dietrich 4 PMID: 32479699. DOI: 10.1111/jth.14930 Abstract Background: Totally implantable venous access ports (TIVAPs) for chemotherapy are associated with venous thromboembolism (VTE). We aimed to quantify the incidence of TIVAP-associated VTE and compare it […]

Central venous catheters and upper extremity deep vein thrombosis in medical inpatients: the Medical Inpatients and Thrombosis (MITH) Study J P Winters 1, P W Callas 1, M Cushman 1, A B Repp 1, N A Zakai 1 PMID: 26340226. DOI: 10.1111/jth.13131 Abstract Background: Upper extremity deep vein thrombosis (UEDVT) is an increasingly recognized complication in medical inpatients, with few data available regarding the incidence, risk factors […]

Incidence of venous thromboembolism and its effect on survival among patients with common cancers Helen K Chew 1, Theodore Wun, Danielle Harvey, Hong Zhou, Richard H White PMID: 16505267. DOI: 10.1001/archinte.166.4.458 Abstract Background: The incidence of venous thromboembolism after diagnosis of specific cancers and the effect of thromboembolism on survival are not well defined. Methods: The California Cancer Registry was linked to the California […]

Incidence of venous thromboembolism in patients undergoing surgical treatment for malignancy by type of neoplasm: An analysis of ACS-NSQIP data from 2005 to 2010 Caroline E Reinke 1, Giorgos C Karakousis, Rachel A Hadler, Jeffrey A Drebin, Douglas L Fraker, Rachel R Kelz PMID: 22828139. DOI: 10.1016/j.surg.2012.05.003 Abstract Introduction: This study investigates the incidence, relative risk, and adjusted odds ratio of venous thromboembolism (VTE) […]

Risk factors for venous thromboembolism Frederick A Anderson Jr 1, Frederick A Spencer PMID: 12814980 DOI: 10.1161/01.CIR.0000078469.07362.E6 Abstract Until the 1990s, venous thromboembolism (VTE) was viewed primarily as a complication of hospitalization for major surgery (or associated with the late stage of terminal illness). However, recent trials in patients hospitalized with a wide variety of acute medical illnesses have […]

Prevention of postoperative deep venous thrombosis and pulmonary emboli with combined modalities M Borow, H J Goldson PMID: 6195948 Abstract Worldwide statistics reveal that 25 to 40 per cent of patients who are over the age of 40 years and operated on for 1 or more hours will develop a deep venous thrombosis (DVT). The studies reviewed […]

Incidence and mortality of venous thrombosis: a population-based study I A Naess 1, S C Christiansen, P Romundstad, S C Cannegieter, F R Rosendaal, J Hammerstrøm PMID: 17367492 DOI: 10.1111/j.1538-7836.2007.02450.x Abstract Background: Estimates of the incidence of venous thrombosis (VT) vary, and data on mortality are limited. Objectives: We estimated the incidence and mortality of a first VT event in a general population. Methods: From the […]

The effect of ankle joint immobilization on lower limb venous flow Johnathan D Craik 1, Amanda Clark 2, James Hendry 2, Andrea H Sott 2, Paul D Hamilton 2 PMID: 25249319. DOI: 10.1177/1071100714552823 Abstract Background: Below-knee cast immobilization is associated with an increased risk of developing deep vein thrombosis secondary to venous stasis. We investigated the effect of weight-bearing in a below-knee cast or pneumatic walking boot […]

Pharmacological thromboprophylaxis to prevent venous thromboembolism in patients with temporary lower limb immobilization after injury: systematic review and network meta-analysis Daniel Horner 1 2, John W Stevens 2, Abdullah Pandor 2, Tim Nokes 3, Jonathan Keenan 3, Kerstin de Wit 4, Steve Goodacre 2 PMID: 31654551. PMCID: PMC7028118. DOI: 10.1111/jth.14666 Abstract Background: Thromboprophylaxis has the potential to reduce venous thromboembolism (VTE) following lower limb immobilization resulting from injury. Objectives: We aimed to estimate the […]

The impact of risk assessment on the implementation of venous thromboembolism prophylaxis in foot and ankle surgery Nikiforos Pandelis Saragas 1, Paulo Norberto Faria Ferrao 2, Evanthia Saragas 3, Barry F Jacobson 4 PMID: 24796824. DOI: 10.1016/j.fas.2013.11.002 Abstract Background: The purpose of this prospective study was to determine whether the more frequently quoted procedure and patient specific risk factors have any impact in the implementation […]

Influence of recent immobilization and recent surgery on mortality in patients with pulmonary embolism D Nauffal 1, M Ballester, R Lopez Reyes, D Jiménez, R Otero, R Quintavalla, M Monreal, RIETE Investigators Collaborators, PMID: 22726525. DOI: 10.1111/j.1538-7836.2012.04829.x Abstract Background: The influence of recent immobilization or surgery on mortality in patients with pulmonary embolism (PE) is not well known. Methods: We used the Registro Informatizado de Enfermedad TromboEmbólica […]