Thromboprophylaxis in Pregnancy

Diana Kolettis ¹, Sabrina Craigo ²

PMID: 29747737. DOI: 10.1016/j.ogc.2018.01.007

Abstract

Venous thromboembolism is a leading cause of maternal morbidity and mortality worldwide. Identifying women who are at greatest risk for venous thromboembolism, and managing their pregnancies with appropriate thromboprophylaxis is essential to decreasing this life-threatening condition. Those at greatest risk are patients with thrombophilias, a personal or family history of venous thromboembolism, and those undergoing cesarean delivery. Current international guidelines on thromboprophylaxis vary in details, but all strategies rely on risk factor identification and thromboprophylaxis for the highest risk patients. All guidelines require clinicians to think critically about individual patient’s risk factors throughout pregnancy and the postpartum period.

Keywords: Pregnancy; Prophylaxis; Thromboembolism; Thromboprophylaxis.

Reference:

Obstet Gynecol Clin North Am. 2018 Jun;45(2):389-402. doi: 10.1016/j.ogc.2018.01.007.